Effect of Aqueous Leaf Extract of Dissotis Roundifolia on Plasma Glucose and Creatinine Concentration in Normal Albino Rats

Dissotis rotundifolia?is a broad spectrum medicinal plant that has received worldwide recognition. This study was designed to investigate the effect of aqueous leaf extract rotundifolia on plasma glucose and creatinine level in normal albino rats. A total 6 wistar rats each weighing 150g were assembled randomly divided into 2 groups (control tests) consisting 3 each. The control group pelleted growers mash distilled water all through period experiment while test 2ml/kg body weight twice daily. Blood samples collected lithium heparin bottle for sodium oxalate tube determination. data obtained subjected statistical analysis using SPSS version 20. Results showed significant increase mean levels treated with compared group. suggests deleterious Dissostis at investigated dosage thus, may not be safe oral consumption. Hence, there is need further studies this regard order ascertain safety rotundifolia.